THE MISSION

Welcome to UCLA's Systems Engineering Laboratory.

Here we utilize the principles of chemical engineering, and mathematics to modify and develop efficient, clean, and flexible
chemical engineering processes.This is accomplished through research in the following areas:

- System Modeling
- Plant Design and Simulation
- Process Optimization and Intensification
- System Control
- System Sustainability and Economic Assessment

RESEARCH

- SYSTEM MODELING:
- PLANT DESIGN & SIMULATION:
- SYSTEM CONTROL:
- SYSTEM SUSTAINABILITY & ECONOMIC ASSESSMENT:

Development of multidimensional models for individual parts and integrated systems through: Computational fluid dynamics (CFD) simulations of multi-phase and multi-scale reacting flow systems and analytical models for the accurate prediction of reactor effluent concentrations.

Design and simulation of novel multi-product and energetic self sufficient chemical plants with zero pollutant emissions through application of reaction clusters, heat and power integration, and state of the art process simulators.

Development of new constrained infinite time optimal control strategies for nonlinear chemical and biochemical units and processes.

Economic profitability and sustainability assessment of intensified modular chemical and biochemical processes, through Life Cycle Assessment (LCA), Techno Economic Analysis (TEA) and newly introduced Sustainability Over Sets (SOS) methodologies.

PEOPLE

SYSTEMS TEAM

Meet Systems Engineering Software Team. Led by Omar Sheikh, the team is compose of a diverse group of majors whose focus is to create software suite for academics and industrial applications.

PUBLICATIONS

2018

2017

2016

2015

2014

2013

2012

2011

2010

1984-2010

Pena Lopez, J. A., Ibubeleye, S., Manousiouthakis, V. I., "Hydrogen/formic acid production from natural gas with zero carbon dioxide emissions", *Journal of Natural Gas Science and Engineering,* Volume 49, January 2018, Pages 84-93

Albassam A, Conner J, Manousiouthakis V. Natural gas derived hydrogen in the presence of carbon fuel taxes and concentrated solar power. ACS Sustainable Chemistry & Engineering. 2018 January 3; 6(3), pp 3029-3038

Da Cruz, F. E., Manousiouthakis, V. I., "Process intensification of reactive separator networks through the IDEAS conceptual framework", *Computers and Chemical Engineering,* Vol. 105, 39-55, October 2017

Pichardo, P., Manousiouthakis, V. I., "Infinite DimEnsionAl State-space as a systematic process intensification tool: Energetic intensification of hydrogen production", *Chemical Engineering Research and Design,* Vol. 120, 372-395, April 2017

Manousiouthakis, V., Jorat M., “Overview of the Existing Sustainability Tools”, Chapter, Encyclopedia of Sustainable Technologies, Martin Abraham Editor, Subhas Sikdar Section Editor, Elsevier, August 2017

Manousiouthakis, V. I., Jorat, M., “Sustainability Over Sets”, *Environmental Progress & Sustainable Energy,* DOI: 10.1002/ep.12761, October 2017

Ibubeleye, S., Manousiouthakis, V. I., "Co-Production of Acetic Acid and Hydrogen/Power from Natural Gas with zero carbon dioxide emissions", *AIChE Journal,* DOI: 10.1002/aic.15966, September 2017

Da Cruz, F. E., Manousiouthakis, V. I., "Parametric studies of steam methane reforming using a multiscale reactor model" *Industrial & Engineering Chemistry Research,* DOI: 10.1021/acs.iecr.7b03253, October 2017

Garshasbi, A., Chen, H., Cao, M., Karagoz, S., Ciora, R. J., Liu, P. K. T., Manousiouthakis, V. I., Tsotsis, T. T., "Membrane-based reactive separations for process intensification during power generation." *Catalysis Today,* October 2017

Manousiouthakis, V. I., "Quantification of Pervasive Environmental Emissions, and Assessment of their Impact on the Environment and Human Health", *COChE Journal,* Editorial Overview: Energy and Environmental Engineering, October 2016

Ghougassian, P., Manousiouthakis, V. I., " Minimum Entropy Generation for Isothermal Endothermic/Exothermic Reactor Networks", *AIChE Journal,* Vol. 61, No.2, 103-117, January 2015

Conner, J., Manousiouthakis, V. I., " Global minimization of an Infinite Collection of Instances of the Total Annualized Cost Problem for Compressor Sequences", *Industrial Engineering Chemistry Research,* Vol. 54, No.6, 1861-1875, January 2015

Agrawal, R., Manousiouthakis, V. I., "Challenges and Solutions for Renewable Energy Use", *COChE Journal,* Editorial Overview: Energy and Environmental Engineering, August 2015

Zayna Al-Husseini, Z., and Manousiouthakis, V. I., " IDEAS based synthesis of minimum volume reactor networks featuring residence time density/distribution models", *Computers & Chemical Engineering 60,* pp. 124-142, 2014

Conner J. A., and Manousiouthakis, V. I., " On the Attainable Region for Process Networks", *AIChE Journal,* Vol. 60, No. 1, 193-212, January 2014

Ghougassian, P., Pena Lopez, J. A., Manousiouthakis, V. I., Smirniotis, P., " CO2 capturing from power plant flue gases: Energetic comparison of amine absorption with MgO based, heat integrated, pressure–temperature-swing adsorption", *International Journal of Greenhouse Gas Control,* 22, pp. 256–271, 2014

Olmos, F., Manousiouthakis, V. I., "Gas Tank Fill-up in Globally Minimum Time: Theory and Application to Hydrogen", *Intern. Journal of Hydrogen Energy,* Vol. 39, No. 23, 12138–12157, 4 August 2014

Conner, J., Manousiouthakis, V. I., " Global optimality properties of total annualized and operating cost problems for compressor sequences", *AIChE Journal,* Vol. 60, No. 12, 4134-4149, December 2014

Olmos, F., Manousiouthakis, V. I., "Hydrogen Car Fill-up Process Modeling and Simulation", *Intern. Journal of Hydrogen Energy,* 38, pp. 3401-3418, January 2013

Ghougassian, P., Manousiouthakis, V. I., " Attainable Composition, Energy Consumption and Entropy Generation Properties for Isothermal/Isobaric Reactor Networks", *Industrial & Engineering Chemistry Research,* 52, pp. 3225-3238, January 2013

Ghougassian, P., Manousiouthakis, V. I., "Globally Optimal Networks for Multipressure Distillation of Homogeneous Azeotropic Mixtures", *Industrial & Engineering Chemistry Research,* 51, No. 34, pp.11183-11200, August 2012

Conner, J., Phillis Y., Manousiouthakis, V. I., "On a Sustainability Interval Index and Its Computation through Global Optimization", *AIChE Journal,* 58, No. 9, pp. 2743-2757, September 2012

Manousiouthakis, V., Thomas, N., Justanieah, A., "On a Finite Branch and Bound Algorithm for the Global Minimization of a Concave Power Law Over a Polytope", *Journal of Optimization Theory and Applications,* 151, No1, pp. 121 – 134, October 2011

Pena Lopez, J. A., Manousiouthakis, V. I., "Natural gas based hydrogen production with zero carbon dioxide emissions", *Intern. Journal of Hydrogen Energy,* 36, No. 20, pp.12853-12868, October 2011

Phillis, Y.A., Kouikoglou V.S., Manousiouthakis, V. I., "A review of sustainability assessment models as system of systems", *IEEE Systems Journal,* 4, No. 1, pp.15 – 25, March 2010

Arkun, Y., Manousiouthakis, B., Palazoglu, A., “Robustness Analysis of Process Control Systems. A Case Study of Decoupling Control in Distillation”, *Ind. Eng. Chem. Proc. Des. Dev.,* 23, pp. 93‑101, 1984.

Arkun, Y., Manousiouthakis, B., Putz, P., “Robust Nyquist Array Methodology: A New Theoretical Framework for Analysis and Design of Robust Multivariable Feedback Systems”, *Int. J. Control,* 40, pp. 603‑629, 1984.

Arkun, Y., Manousiouthakis, B., Palazoglu, A., Putz, P., Guruswamy, V., Putz, P., “Computer‑Aided Analysis and Design of Robust Multivariable Control Systems for Chemical Processes”, *Computers & Chemical Engineering,* 9, No. 1, pp. 27‑59, 1985.

Palazoglu, A., Manousiouthakis, B., Arkun, Y., “Design of Chemical Plants with Improved Dynamic Operability in an Environment of Uncertainty”, *Ind. Eng. Chem. Proc. Des. Dev.,* 24, pp. 802‑813, 1985.

Manitius, A., Manousiouthakis, V., “On Spectral Controllability of Multi‑Input Time-Delay Systems”, *Sys. & Control Letters,* 6, No. 3, pp. 199‑205, 1985.

Manousiouthakis, V., Savage, B, Arkun, Y., “Synthesis of Decentralized Control Structures and the Block Relative Gain Concept”, *AIChE J.,* 32, No. 6, pp. 991‑1003, 1986.

Nett, C., and Manousiouthakis, V., “Euclidean Condition and Block Relative Gain: Connections, Conjectures and Clarifications”, *IEEE Trans. Auto Control,* AC‑32, No. 5, pp. 405‑407, 1987.

Manousiouthakis, V., and Arkun, Y., “A Hybrid Approach for the Design of Robust Control Systems”, *Int. J. Control,* Vol. 45, No. 6, pp. 2203‑2220, 1987.

Manousiouthakis, Vasilios, “Robust Control. An Overview and Some New Directions”, The First Shell Process Control Workshop, D. Prett and M. Morari, Eds., pp. 213-223, Butterworths, 1987.

Manousiouthakis, V., and Nikolaou, M., “Analysis of Decentralized Control Structures for Nonlinear Systems”, *AIChE J.,* Vol. 35, pp. 549‑559, 1989.

Nikolaou, M. and Manousiouthakis, V., “A Hybrid Approach to Nonlinear System Stability and Performance”, *AIChE J.,* Vol. 35, pp. 559‑573, 1989.

El‑Halwagi, M. and Manousiouthakis, V., “Synthesis of Mass Exchange Networks”, AIChE J., Vol. 35, pp. 1233‑1245, 1989.

Manousiouthakis, V., “A Game Theoretic Approach to Robust Controller Synthesis”, Special Control Issue, *Computers and Chemical Engineering,* Vol. 14, pp. 381-389, 1990.

Manousiouthakis, Vasilios, “A Game Theoretic Approach to Robust Control Synthesis and the Shell Control Problem”, The Second Shell Process Control Workshop, D. Prett, C. Garcia and B. Ramaker, Eds., pp. 291-313, Butterworths, 1990.

El-Halwagi, M. and Manousiouthakis, V., “Automatic Synthesis of Mass Exchange Networks with Single Component Targets”, *Chemical Engineering Science,* Vol. 45, No. 9, pp. 2813-2831, 1990.

El-Halwagi, M. and Manousiouthakis, V., “Simultaneous Synthesis of Mass Exchange and Regeneration Networks”, *AIChE Journal,* Vol. 36, No. 8, pp. 1209-1219, 1990.

Behmanesh, N., Manousiouthakis, V., Allen, D., “Optimizing the Throughput of Hazardous Waste Incinerators”, *AIChE Journal,* Vol. 36, No. 11, pp. 1707-1714, 1990.

Nikolaou, M. and Manousiouthakis, V., “Sensitivity Analysis of Optimal Control Policies for Batch Processes”, *Chemical Engineering Communications,* Vol. 90, pp. 27-45, 1990.

Bagajewicz, M., and Manousiouthakis, V., “On the Generalized Benders Decomposition”, *Computers and Chemical Engineering*, Vol. 5, No. 10, pp. 691-700, 1991.

Manousiouthakis, V., and Sourlas, D., “A Global Optimization Approach to Rationally Constrained Rational Programming”, *Chemical Engineering Communications,* Vol. 115, pp. 127-147, 1992.

Manousiouthakis, V., “On Doubly Coprime Fractional Representations for Linear Time-Varying Systems”, *IEEE Transactions on Automatic Control,* Vol. AC-37, No. 3, pp. 412-416, 1992.

Bagajewicz, M., and Manousiouthakis, V., “On the Mass/Heat Exchange Network Representation of Distillation Networks”, *AIChE Journal,* 38(11), 1769-1800, November 1992.

El-Halwagi, M., El-Halwagi, A., and Manousiouthakis, V., “Optimal Design of Recycle/Reuse Networks for the Dephenolization of Petroleum Refinery Wastes”, *Trans. Inst. Chem. Eng.,* Vol. 70, Part B, pp. 131-139, 1992.

Gupta, A., and Manousiouthakis, V., “Minimum Utility Consumption for Mass Exchange Networks with Variable Single Component Supplies and Targets”, *Industrial and Engineering Chemistry,* Vol. 32, No. 9, 1937-1950, 1993.

Wilcoxson, M., and Manousiouthakis, V., “Well-Posedness of Continuum Modeling for Weakly Ionized Plasmas”, *IEEE Transactions on Plasma Science,* Vol. 21, No. 2, pp. 213-222, 1993.

Manousiouthakis, V., “On the Parametrization of All Decentralized Stabilizing Controllers”, *Systems and Controls Letters,* Vol. 21, pp. 397-403, 1993.

Wilcoxson, M., and Manousiouthakis, V., “On an Implicit ENO Scheme”, Journal of Computational Physics, Vol. 115, No. 2, pp. 376-389, 1994.

Manousiouthakis, V., and Sourlas, D., “Discussion on a Reactor Optimization Problem”, Chemical Engineering Communications, Vol. 130, pp. 139-142, 1994.

Gupta, A., and Manousiouthakis, V., “Waste Reduction through Multicomponent Mass Exchange Network Synthesis”, *Computers and Chemical Engineering*, Vol. 18S, pp. S585-S590, 1994.

Sourlas, D., Manousiouthakis, V., “Best Achievable Decentralized Performance”, *IEEE Transactions on Automatic Control,* Vol. 40, No. 11, pp. 1858-1871, 1995.

Gupta, A., and Manousiouthakis, V., “An Underwood-Like Mass Exchanger Model”, *AIChE Journal,* Vol. 41, No. 8, pp. 1843-1851, 1995.

Manousiouthakis, V., Allen, D., “Process Synthesis for Waste Minimization”, Foundations of Computer Aided Process Design, *AIChE Symposium Series,* 91:72-86, 1995.

Gupta, A., Manousiouthakis, V., “Variable Target Mass-Exchange Network Synthesis through Linear Programming”, *AIChE Journal,* Vol. 42, No. 5, pp. 1326-1340, 1996.

Wilcoxson, M., and Manousiouthakis, V., “Simulation of a Three Moment Fluid Model of a Two Dimensional Radio Frequency Discharge”, *Chemical Engineering Science,* Vol. 51, No. 7, pp. 1089-1106, 1996.

Choi, J., and Manousiouthakis, V., “On the Parametrization of Nonlinear Finite Gain over Set Stabilizing Controllers”, *Systems and Control Letters,* Vol. 28, pp.173-179, 1996.

Manousiouthakis, V. and El-Halwagi, A., El-Halwagi, M., “Analysis and Simulation of Hollow-Fiber Reverse-Osmosis Modules”, *Separation Science and Technology,* Vol. 31, No. 18, pp.2505-2529, 1996.

Chmielewski, D., Manousiouthakis, V., “On Constrained Infinite-Time Linear Quadratic Optimal Control”, *Systems and Control Letters,* Vol. 29, pp. 121-129, 1996.

Phillis, Y., Kouikoglou, V., Sourlas, D. and Manousiouthakis, V. “Design of Serial Production Systems Using Discrete Event Simulation and Non-convex Programming Techniques”, *Int. J. Prod.Res.,* Vol. 35, No. 3, pp. 753-766, 1997.

Han, JR; Manousiouthakis, V; Choi, SH. “Global optimization of chemical processes using the interval analysis”, *Korean Journal of Chemical Engineering,* Vol.14, No.4, pp.270-276, Jul. 1997.

Sourlas, D., Choi, J., and Manousiouthakis, V., “Optimal Feedback Control of SISO Saturation Systems over a Class of Nonlinear Stabilizing Controllers”, *International Journal of Nonlinear and Robust Control,* Vol. 7, pp. 449-474, 1997.

Holiastos, K., Manousiouthakis, V., “Automatic Synthesis of Thermodynamically Feasible Reaction Clusters”, *AIChE Journal,* Vol. 44, No.1, pp. 164-173, Jan 1998.

Vaidyanathan, R., Wilks, T., Wilson, S., Manousiouthakis, V., “Cost-Effective Design of Clean Chemical Processes by the Application of Mass Integration Tools”, *Hydrocarbon Processing,* Vol. 77, No. 4, p.79+, Apr. 1998.

Bagajewicz, M., Pham, R., and Manousiouthakis, V., “On the State-Space Approach to Mass/Heat Exchanger Network Design”, *Chemical Engineering Science,* Vol. 53, No. 14, pp. 2595-2621, Jul 1998.

Edwards, K., Edgar, T.F., Manousiouthakis, V., “Kinetic model reduction using genetic algorithms”, *Computers and Chemical Engineering*, Vol. 22, No. 1-2, pp. 239-246, 1998.

Ziaka, Z., Manousiouthakis, V., “Best Achievable Reversible Reaction Conversion in a Membrane Reactor”, *Industrial and Engineering Chemistry,* Vol. 37, No. 9, pp. 3551-3560, Sep. 1998.

Kim, H., Manousiouthakis, V., “Dually Driven Radio Frequency Plasma Simulation with a Three Moment Model Simulation of a triode plasma reactor”, *Journal of Vacuum Science and Technology A,* Vol.16, No. 4, pp. 2162-2172, Aug 1998.

Wilson, S., Manousiouthakis V., “Minimum Utility Cost for a Multi-Component Mass Exchange Operation”, *Chemical Engineering Science,* Vol. 53, No. 22, pp. 3887-3896, Nov. 1998.

Manousiouthakis, V. I.; Deem, M. W., “Strict detailed balance is unnecessary in Monte Carlo simulation”, *Journal of Chemical Physics,* Vol. 110, No. 6, pp. 2753-2756, Feb. 1999.

Sourlas, D., Manousiouthakis, V., “Best achievable performance: Non-switching compensation for multiple models”, *International Journal of Robust and Nonlinear Control,* Vol. 9, No. 9, pp. 521-549, Jul. 1999.

Chmielewski, D., Ziaka, Z., Manousiouthakis, V. I., “Conversion targets for plug flow membrane reactors”, *Chemical Engineering Science,* Vol. 54, No.13-14, pp. 2979-2984, Jul. 1999.

Holiastos, K., Manousiouthakis, V. I., “Minimum hot-cold and electric utility cost for a finite-capacity reservoir system”, *Computers and Chemical Engineering*, Vol. 23, No. 9, pp. 1263-1276, Nov. 1999.

Choi, S. H., Ko, J. W., Manousiouthakis, V. I., “A stochastic approach to global optimization of chemical processes, *Computers and Chemical Engineering*, Vol. 23, No. 9, pp. 1351-1356, Nov. 1999.

Kim, H. C., Manousiouthakis, V. I., “Simulation based plasma reactor design for improved ion bombardment uniformity, *Journal of Vacuum Science and Technology B,* Vol.18, No. 2, pp.841-847, Mar./Apr. 2000.

Edwards, K., Edgar, T.F., Manousiouthakis, V. I., “Reaction mechanism simplification using mixed-integer nonlinear programming”, *Computers & Chemical Engineering,* Vol. 24, No. 1, pp.67-79, Apr. 2000.

Chmielewski, D. J., Manousiouthakis, V. I., Tilton, B., Felix, B., “Loss accounting and estimation of leaks and instrument biases using time-series”, *Industrial & Engineering Chemistry,* Vol. 39, No. 7, pp. 2336-2344, Jul. 2000.

Choi, J., Manousiouthakis, V. I., “On a Measure of Bounded Input/Initial State Bounded Output Stability Over Ball”, *Chemical Engineering Science,* Vol. 55, No. 24, pp. 6059- 6070, Dec 2000.

Wilson, S., Manousiouthakis, V. I., “IDEAS approach to process network synthesis: Application to multi-component MEN”, *AIChE Journal,* Vol.46, No.12, pp.2408-2416, Dec. 2000.

Manousiouthakis, V. I., “Energy and the Environment”, AIChE Topical Conference Proceedings, V. I. Manousiouthakis, Chair, *AIChE Publications,* 2000.

Kim, H. C., Manousiouthakis, V. I., “Dust transport phenomena in a capacitively coupled plasma reactor”, *Journal of Applied Physics,* Vol. 89, No. 1, pp. 34-41, Jan. 2001.

Kim, H. G., Choi, S. H., Manousiouthakis V., “A Method for Automatic Synthesis of Reaction Clusters Incorporating Thermodynamic and Separability Criteria”, *Theories and Applications of Chemical Engineering,* Vol. 7, No. 2, pp.3159-3162, 2001

Martin, L. L., Manousiouthakis, V. I., “Total annualized cost optimality properties of state-space models for mass and heat exchanger networks”, *Chemical Engineering Science,* Vol. 56, No. 20, pp. 5835-5851, Oct. 2001.

Manousiouthakis, V. I., Chmielewski, D. J., “On constrained infinite-time nonlinear optimal control”, *Chemical Engineering Science,* Vol. 57, No. 1, pp. 105-114, Jan. 2002.

Holiastos, K., Manousiouthakis, V. I., “Minimum hot/cold/electric utility cost for heat exchange networks”, *Computers & Chemical Engineering,* Vol. 26, No. 1, pp. 3-16, Jan. 2002.

Choi, S. H., Manousiouthakis, V. I., “Global Optimization Methods for Chemical Process Design: Deterministic and Stochastic Approaches”, *Korean Journal of Chemical Engineering,* Vol. 19, No. 2, pp. 227-232, 2002

Chmielewski, D. J., Lopez T., Manousiouthakis V. I., “On the Theory of Optimal Sensor Placement”, *AIChE Journal,* Vol. 48, No. 5, pp. 1001-1012, May 2002

Burri, J.F., Wilson, S. D., Manousiouthakis, V. I., “Infinite Dimensional State-space approach to reactor network synthesis: application to attainable region construction”, *Computers & Chemical Engineering,* Vol. 26, No. 6, pp. 849-862, 2002

Drake, J. E., Manousiouthakis, V. I., “IDEAS Approach to Process Network Synthesis: Minimum Utility Cost for Complex Distillation Networks”, *Chemical Engineering Science,* Vol. 57, No. 15, pp. 3095-3106, August 2002

Drake, J. E., Manousiouthakis, V. I., “IDEAS Approach to Process Network Synthesis: Minimum Plate Area for Complex Distillation Networks with Fixed Utility Cost”, *Industrial and Engineering Chemistry Research,* Vol. 41, No. 20, pp. 4984-4992, October 2002

Justanieah, A. M., Manousiouthakis, V. I., “IDEAS Approach to the Synthesis of Globally Optimal Separation Networks: Application to Chromium Recovery from Wastewater”, *Advances in Environmental Research,* Vol. 7, No. 2, pp. 549-562, January 2003

Martin, L., Manousiouthakis, V. I., “Globally Optimal Power Cycle Synthesis via the Infinite-DimEnsionAl State-space (IDEAS) Approach Featuring Minimum Area with Fixed Utility”, *Chemical Engineering Science,* Vol. 58, No. 18, pp. 4291-4305, September 2003

Chen, Y., Edgar, T., Manousiouthakis, V. I., “On Infinite-time Nonlinear Quadratic Optimal Control”, *Systems and Control Letters,* Vol. 51, No. 3-4, pp. 259-268, March 2004

Kim, H. C., Sul, Y. T., Manousiouthakis, V.I., "On rapid computation of time periodic steady state in simulation of capacitively coupled RF plasma", *IEEE Trans. on Plasma Science,* Vol. 32, No. 2 Part 1, pp. 399-404, April 2004

Manousiouthakis, V., Martin, L. L., "A minimum area (MA) targeting scheme for single component MEN and HEN synthesis", *Computers & Chemical Engineering,* Vol. 28, No. 8, pp. 1237-1247, July 2004

Manousiouthakis, V. I., Justanieah, A. M., Taylor, L. A., “The Shrink-Wrap Algorithm for the Construction of the Attainable Region: an Application of the IDEAS Framework”, *Computers and Chemical Engineering*, Vol. 28, No. 9, pp. 1563-1575, August 2004

Burri, J. E., Manousiouthakis V. I., “Global Optimization of reactive distillation networks using IDEAS”, *Computers & Chemical Engineering,* Vol. 28, No. 12, pp. 2509-2521, November 2004

Holiastos, K., Manousiouthakis V. I., “Infinite-Dimensional state-space (IDEAS) approach to globally optimal design of distillation networks featuring heat and power integration”, *Industrial & Engineering Chemistry Research,* Vol.43, No. 24, pp.7826-7842, November 2004

Chmielewski, D. J., Manousiouthakis, V., “On constrained infinite-time linear quadratic optimal control with stochastic disturbances”, *Journal of Process Control,* Vol. 15, No. 4, pp. 383-391, June 2005

Posada, A., Manousiouthakis, V., “Heat and power integration of methane reforming based hydrogen production”, *Industrial & Engineering Chemistry Research,* Vol.44, No. 24, pp.9113-9119, November 2005

Chen, Y., Edgar, T., Manousiouthakis, V. I., “Globally optimal nonlinear feedback: application to nonisothermal CSTR control”, *Chemical Engineering Communications,* 193, No. 2, pp. 233-245, February 2006.

Posada, A., Manousiouthakis, V., “Hydrogen and dry ice production through phase equilibrium separation and methane reforming”, *Journal of Power Sources,* 156, No. 2, pp. 480-488, June 2006

Chen, I. K., Winnick, J., Manousiouthakis V., “Global Optimization of a Simple Mathematical Model for a Proton Exchange Membrane Fuel Cell”, *Computers and Chemical Engineering*, 30, No. 6, pp. 1226-1234, June 2006

Posada, A., Kim, Y. I., Manousiouthakis, V., “On conduction-cooling of a high-temperature superconducting cable”, *Cryogenics,* 46, No. 6, pp. 458-467, June 2006

Zhou, W., Manousiouthakis, V., “Non-ideal reactor Network Synthesis through IDEAS: Attainable region construction”, *Chemical Engineering Science,* 61, No. 21, pp. 6936-6945, November 2006

Zhou, W., Manousiouthakis, V. I., “Pollution prevention through reactor network synthesis: the IDEAS approach”, *International Journal Of Environment And Pollution,* 29, No.1-3, pp. 206-231, 2007

Zhou, W., Manousiouthakis, V. I., “Variable density fluid reactor network synthesis - Construction of the attainable region through the IDEAS approach”, *Chemical Engineering Journal,* 129, No. 1-3, pp. 91-103, May 2007

Zhou, W., Manousiouthakis, V. I., “On dimensionality of attainable region construction for isothermal reactor networks”, *Computers and Chemical Engineering*, 32, No. 3, pp. 439-450, March 2008

Mohsen-Nia, M., Mohammad Doulabi, F.S., Manousiouthakis, V.I., "(Liquid + liquid) equilibria for ternary mixtures of (ethylene glycol + toluene + n-octane)", *Journal of Chemical Thermodynamics,* 40, No. 8, pp. 1269-1273, March 2008

Zhou, W., Manousiouthakis, V. I., “Global Capital/Total Annualized Cost Minimization of Homogeneous and Isothermal Reactor Networks”, Industrial & Engineering Chemistry Research, 47, No. 10, pp. 3771-3782, April 2008

Davis, B. J., Taylor, L. A., Manousiouthakis, V. I., " Identification of the Attainable Region for Batch Reactor Networks", *Industrial & Engineering Chemistry Research,* 47, No. 10, pp. 3388-3400, April 2008

Posada, A., Manousiouthakis, V. I., "Multi-feed attainable region construction using the Shrink–Wrap algorithm", *Chemical Engineering Science,* 63, No. 23, pp. 5571-5592, July 2008

Zhou, W., Manousiouthakis, V. I., “Automating the AR construction for non-isothermal reactor networks”, *Computers and Chemical Engineering*, 33, No. 1, pp. 176–180, January 2009

Contact

Vasilios I. Manousiouthakis

Tel: +1 (310) 206-0300

vasilios@ucla.edu

Dept. of Chemical & Biochemical Engineering

5549 Boelter Hall

University of California, Los Angeles

Los Angeles, CA 90025