UCLA Optofluidics Systems Laboratory

Journal Papers
28	Ting-Hsiang Wu , Yue Chen , Sung-Yong Park , Jason Hong , Tara Teslaa , Jiang F. Zhong , Dino Di Carlo , Michael A. Teitell and Pei-Yu Chiou “Pulsed laser triggered high speed microfluidic fluorescence activated cell sorter," Lab on a Chip, Vol 12, pp 1378-1383, 2012. (Research highlight in Nature Photonics in May 2012)
27	Yue Chen, Ting-Hsiang Wu and Pei-Yu Chiou., “Scanning Laser Pulses Driven Microfluidic Peristaltic Membrane Pump," Lab on a Chip, Vol 12, DOI: 10.1039/C2LC40079K, 2012
26	Park, S., Chiou, P. Y., “Light-driven Droplet Manipulation Technologies for Lab-on-a-Chip Applications," Advances in Optoelectronics, Vol 2011, Article ID 909174, 12 pages, 2011. (Special issue: Optofluidics for Lab on Chip).
25	Huang, K.-W., Sattar, S., Zhong, J., Chou, C.-H., Tsai, H.-K., Chiou, P. Y. “Electrodes for Microfluidic Integrated Optoelectronic Tweezers,” Advances in Optoelectronics, Vol 2011, Article ID 375451, 10 pages, 2011. (Special issue: Optofluidics for Lab on Chip).
24	Frencha, C. T., Toescaa, I. J., Wu, T.-H., TeSlaac, T, Beatya, S. M., Wonga, W., Liua, M. H, Schrodera, I. S., Chiou, P. Y., Teitell, M. A., Miller, J. F.,” Dissection of the Burkholderia intracellular lifecycle using a photothermal nanoblade,” Proceedings of the National Academy of Sciences, Vol 108, pp 12095–12100, 2011.
23	Wu, T.-H., Teslaa, T., Kalim, S., French, C. T., Maghadam, S., Wall, R., Miller, J. F., Witte, O. N., Teitell, M., and Chiou, P. Y., “Photothermal nanoblade for large cargo delivery into live mammalian cells,” Analytical Chemistry, 83, pp 1321–1327, 2011. (highlighted in Chemical & Engineering News: Cargo Delivery To Cells Gets Supersized) (Selected as JALA Top Ten Innovation in 2011)
22	Park, S., Wu, T.-H., Chen, Y., Chiou, P. Y., “Pulse laser driven ultrafast droplet generation on demand,” Lab on a Chip, 11, pp. 1010 - 1012, 2011. (Selected as Lab Chip HOT article: Precise, high speed droplet formation )
21	Wu, T.-H., Teslaa, T., Teitell, M., Chiou, P. Y., “Photothermal nanoblade for patterned membrane cutting," Optics Express, Vol. 18, pp. 23153-23160 , 2010.
20	Xiao, F., Wu, T.-H., Chiou, P. Y., “Near field photothermal printing for rapid fabrication of gold microstructures and nanostructures,”Applied Physics Letter, Vol 97, pp. 031112, 2010.
19	Park, S., Teitell, M. A., Chiou, P. Y., “Light patterned continuous electrowetting on a single photoconductive surface,” Lab on a Chip, Vol 10, pp 1633-1740, 2010. (Selected as inside cover paper)
18	Wang, S., Chen, K.-J., Wu, T.-H., Wang, H., Lin, W.-Y., Ohashi, M., Chiou, E. P. Y., Tseng, H.-R.,“Photothermal Effects of Supramolecularly Assembled Gold Nanoparticles for Targeted Treatment of Cancer Cells,” Angewandte Chemie, Vol 49, pp. 3777 – 3781, 2010.
17	Hsu, H.-Y., Ohta A. T., Chiou, P. Y., Jamshidi, A., Neale, S. L., Wu, M. C.” Phototransistor-based optoelectronic tweezers for dynamic cell manipulation in cell culture media,” Lab on a Chip, Vol. 10, pp.165 - 172, 2009.
16	Lau, A. N. K. Lau, Ohta, A. T., Phan, H. L., Hsu, H.-Y., Jamshidi, A., Chiou, P. Y. Wu, M. C., “Antifouling coatings for optoelectronic tweezers,” Lab on a Chip, Vol. 9, pp. 2952 - 2957, 2009
15	Wu, T. H., Kalim, S., Callahan, C., Teitell, M., Chiou, P. Y. “Image Patterned Molecular Delivery into Live Cells Using Gold Particle Coated Substrates,” Optics Express, Vol. 18, Issue 2, pp. 938-946, 2009. (Selected to be published on the Virtual Journal for Biomedical Optics)
14	S. Park, S. Kalim, C. Callahan, M. Teitell, P. Y. Chiou, “A light-induced dielectrophoretic droplet manipulation platform,” Lab on a Chip, Vol. 9, pp. 3228–3235, 2009.
13	G. J. Shah, A. T. Ohta, P. Y. Chiou, M. C. Wu, C. J. Kim, ”EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis,” Lab on a Chip, 9, pp. 1732–1739, 2009.
12	K. Mehta, T.-H. Wu, P. Y. Chiou, “Magnetic Nanowire Enhanced Optomagnetic Tweezers,” Applied Physics Letter, Vol. 93, pp. 254102, Vol 2008. (article selected for Virtual Journal of Nanoscale Science & Technology)
11	T.-H. Wu, L. Gao, Y. Chen, K. Wei, P. Y.Chiou, “Pulse Laser Trigger High Speed Microfluidic Switch,” Applied Physics Letter, Vol. 93, pp. 144102, 2008. (article selected for the October 20, 2008 issue of Virtual Journal of Nanoscale Science & Technology)
10	P. Y. Chiou, S. Park, M. C. Wu, “Continuous optoelectrowetting for picoliter droplet manipulation,” Applied Physics Letter,Vol 93, 221110, 2008. (Article highlight in Nature Photonics)
9	P. Y. Chiou, Ting-Hsiang Wu, “Laser guided drug delivery and therapy,” IEEE Nanomedicine, 2008. (Invited Paper)
8	P. Y. Chiou, Zehao Zhang, M. C. Wu,” Droplets Manipulation with Light on Optoelectrowetting Device,” Journal of Microelectromechanical Systems, Vol. 17 pp. 133-138, 2008.
7	P. Y. Chiou, Aaron T. Ohta, Arash Jamshidi, Hsan-Yin Hsu, M. C. Wu,” Light Image Patterned Microfluidic Vortices for Parallel Nanoparticle Trapping and Transport,”Journal of Microelectromechanical Systems, Vol. 17, pp 525-531, 2008.
6	S. Park, C. Pan, E. P. Y. Chiou, T.-H. Wu, C. Kloss, S., Kalim, C. E. Callahan, M. Teitell, “Floating electrode optoelectronic tweezers (FEOET): Light Driven Droplet Manipulation in Electrically Insulating Oil,” Applied Physics Letter, Vol. 92, pp. 151101, 2008. (Article highlight in Nature Photonics)
5	Arash Jamshidi, Peter J. Pauzauskie, P. James Schuck, Aaron Ohta, P. Y. Chiou, J. Chou, Peidong Yang, and Ming C. Wu ,” Dynamic manipulation and separation of individual semiconducting and metallic nanowires,” Nature Photonics, vol. 2, pp. 86-89, 2008. (Cover Paper)
4	A. T. Ohta, P. Y. Chiou, H. L. Phan, S. W. Sherwood, J. M. Yang, A. N. K. Lau, H. Y. Hsu, A. Jamshidi, M. C. Wu,” Optically Controlled Cell Discrimination and Trapping Using Optoelectronic Tweezers,” Journal of Selected Topics in Quantum Electronics, vol. 13, pp.235-243, 2007.
3	Aaron T. Ohta, P. Y. Chiou, M. C. Wu,” Dynamic Microparticle Control via Optoelectronic Tweezers,” Journal of Microelectromechanical Systems, vol. 16 , pp. 491-499, 2007.
2	P. Y. Chiou, Aaron T. Ohta, Ming C. Wu,” Massively parallel manipulation of single cells and microparticles using optical images," Nature, vol. 436, pp. 370-372, 2005.
1	P. Y. Chiou, H. Moon, H. Toshiyoshi, C.J. Kim, M. C. Wu, “Light actuation of liquid by Optoelectrowetting,” Sensors & Actuators A-Physical, vol. 104, pp. 222-228, 2003.

Conference Papers
44	Wu, T.-H., Teslaa, T., Teitell, M. A., Chiou, P. Y. “ Photothermal nanoblade for single cell surgery,” in proceeding of the IEEE 23th Annual International Conference on Micro Electro Mechanical Systems (MEMS ‘11), pp. 1055-1058, 2011.
43	Chen, Y., Wu, T.-H., Chiou, P. Y.” Driving multilayer PDMS based peristaltic pump with laser pulses,” in proceeding of the IEEE 23th Annual International Conference on Micro Electro Mechanical Systems (MEMS ‘11), pp. 1111-1114, 2011.
42	Park, S., Wu, T.-H. Chen, Y., Nisperos, S., Zhong, J. Chiou, P. Y. “A pulse laser driven microfluidics device for ultrafast droplet generation on demand and single cell encapsulation” The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS), pp1-3, 2010
41	Wu, T-H., Chen, Y., Hur, S. C., Carlo, D. D., Chiou, P. Y. “Pulsed Laser Triggered High Speed Fluorescence Activated Microfluidic Switch” IEEE/LEOS International Conference on Optical MEMS and Nanophotonics, pp. 1-2, Aug 2010.
40	Xiao, F., Chiou, P. Y., “Reshaping Gold Micro and Nano Structures with Polarization Dependent Photothermal Annealing” IEEE/LEOS International Conference on Optical MEMS and Nanophotonics, pp. 1-2, Aug 2010.
39	Park, S., Wu, T.-H. Chen, Y., Chiou, P. Y. “A Laser Driven Optofluidic Device for High-speed and Precise Volume-Controlled Droplet Generation on Demand” IEEE/LEOS International Conference on Optical MEMS and Nanophotonics, pp. 1-2, Aug 2010.
38	Chiou, P. Y., Wu, T.-H., Park, S, “Pulse laser driven ultrafast micro and nanofluidics systems,” SPIE, pp. 1-8, Aug 2010.
37	F. Xiao, T.-H. Wu, P. Y. Chiou, “Near Field Photothermal Annealing for Rapid Laser Printing of Metallic Micro and Nano Structures,” in Proceeding of Solid-State Sensor, Actuator, and Microsystems Workshop (HH ’10), pp.1-4, June 2010.
36	T.-H. Wu, F. Xiao, S. Kalim, T. Teslaa, M. A. Teitell, P. Y. Chiou, “Molecular delivery into live cells using gold nanoparticle arrays fabricated by polymer mold guided near-field photothermal annealing,” ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, Houston, TX, pp. 1-2, February 2010.
35	T.-H. Wu, F. Xiao, M. A. Teitell, P. Y. Chiou, “Molecular delivery into live cells using gold nanoparticle coated substrates fabricated by pulsed laser annealing,” SPIE Photonics West BioS, San Francisco, CA, pp.1-7, January 2010.
34	X. Fan, T. H. Wu, P. Y. Chiou, “Rapid fabrication of periodic metallic nanostructures using polymer mold guided near field photothermal annealing,” in the Proceeding of the Seventeenth Annual International Conference of Composite/Nano Engineering, pp. 1-2, July 2009.
33	K. W. Huang, P. Y. Chiou, “ Optoelectronic Tweezers Integrating with Lensless Imaging for Wide Field Interactive Optical Manipulation,” in Proceeding of IEEE/LEOS International Conference on Optical MEMS and Nanophotonics, pp. 1-2, August 2009.
32	S. Park, P. Y. Chiou, "Single-Side Continuous Optoelectrowetting (SCOEW) for Light-Actuated, Volume-Controlled Droplet Injection, Transportation and Mixing" to be published in the Proceeding of uTAS 2009.
31	K. W. Huang, T. H. Wu, J. F. Zhong, P. Y Chiou, Microfluidic integrated optoelectronic tweezers, in Proceedings of IEEE International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers ’09), pp. 1-4 June 2009. (to be published)
30	T.-H. Wu, S. Kalim, C. Callahan, M. A. Teitell, P. Y. Chiou,” Laser Triggered High Speed Micro and Nano fluidics for Biomedical Applications,” in the proceeding of the 4th Asian and Pacific Rim Symposium on Biophotonics, pp. 1-2 May 27, 2009.
29	T-H Wu, S. Kalim, T. TeSlaa, C. Callahan, P.-Y. Chiou, and M. A. Teitell, “Developing a Biophotonic Approach for Gene Transfer into Prostate Stem and Precursor Cells,” the American Association of Cancer Research special meeting on prostate cancer in San Diego, 2009.
28	K. Mehta, T.-H. Wu, P. Y. Chiou, “Magnetic Nanowire Enhanced Optomagnetic Tweezers,” in Proceeding of IEEE NEMS 2009 Conference, 2009.
27	T. H. Wu, L. Gao, K. Wei, P. Y. Chiou, “Pulse Laser Triggered High Speed Microfluidic Switch,” in Proceeding of IEEE/LEOS International Conference on Optical MEMS and Nanophotonics, August 2008. (to be published)
26	S. Kalim, T. H. Wu, C. Callahan, P. Y. Chiou, M. Teitell " Molecular delivery into live cells with light image patterns and a gold particle coated substrate," in proceeding of the 11th international conference on miniaturized systems for chemistry and life science (uTAS), San Diego, USA, Oct 2008. ( To be published)
25	T. H. Wu, S. Kalim, M. Teitell, P. Y. Chiou " Light image patterned molecular delivery into live cells using gold particle coated substrate," July 2008. ( To be published)
24	S. Park, T.-H. Wu, S. Kalim, C. E. Callahan, M. Teitell and P. Y. Chiou “ Optical Image Based Dynamic Manipulation of Aqueous Droplets Immersed in Oil Medium,” to be published of Solid-State Sensor, Actuator, and Microsystems Workshop (HH ’08), June 2008
23	P. Y. Chiou, Ming C. Wu “Manipulating Nanoparticles and Macromolecules with Light Patterned Microfluidic Flow” in Proceeding of IEEE NEMS 2008 Conference, 2008. (Invited Paper).
22	Chenlu Pan, Sungyong Park, Lanyu Gao, P. Y. Chiou, “Dynamic Magnetic Manipulation using electric field addressed ferrofluidic droplets,” in Proceeding ofIEEE 20th Annual International Conference on Micro Electro Mechanical Systems (MEMS ‘08), 2008.
21	Ming C. Wu, P.-Y. Chiou, “Optofluidics and Optoelectronic Tweezers,” in Proceedings of the 13th Microoptics Conferenece, pp. 104-107, Oct. 2007. (Invited paper)
20	T.-H. Wu, P.-Y. Tseng, S. Kalim, M. Teitell and P.-Y. Chiou, “A Novel Single-Cell Surgery Tool Using Photothermal Effects of Metal Nanoparticles,” submitted to IEEE/LEOS International Conference on Optical MEMS and Nanophotonics, pp. 43-44, August 2007.
19	S. Park, C. Pan, T.-H. Wu, S. Kalim, M. Teitell and P. Y. Chiou,” Floating Electrode Optoelectronic Tweezers (FEOET): A Novel Mechanism Enabling Optical Manipulation of Oil Immersed Aqueous Droplets,” to be published in Proceeding of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS) in Paris, France, October 2007.
18	H.-Y. Hsu, A. T. Ohta, P. Y. Chiou, A. Jamshidi, M. C. Wu,” Phototransistor based optoelectronic tweezers for cell manipulation in highly conductive solution,” in Proceedings of IEEE International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers ’07), June 2007.
17	A. Jamshidi, P. J. Pauzauskie, Aaron T. Ohta, P. Y. Chiou, H.-Y. Hsu, P. Yang, M. C. Wu,” Semiconductor Nanowire Manipulation Using Optoelectronic Tweezers,” in Proceedings of IEEE 19th Annual International Conference on Micro Electro Mechanical Systems (MEMS ‘07), 2007.
16	Aaron T. Ohta, P. Y. Chiou, A. Jamshidi, H.-Y. Hsu, M. C. Wu, “Spatial Cell Discrimination Using Optoelectronic Tweezers,” accepted for IEEE LEOS Summer Topical on Optofluidics, 2006.
15	Aaron T. Ohta, P. Y. Chiou, A. Jamshidi, H.-Y. Hsu, M. C. Wu, “Optically Controlled Manipulation of Live Cells using Incoherent Light Driven Optoelectronic Tweezers,” in Proceedings of SPIE - the International Society for Optical Engineering, 2006.(Invited Paper).
14	P. Y. Chiou, Aaron T. Ohta, A. Jamshidi, H.-Y. Hsu, J. B. Chou, M. C. Wu,”Light Actuated AC Electroosmosis for Optical Manipulation of Nanoscale Particles,” to be published in Proceedings of Solid-State Sensor, Actuator, and Microsystems Workshop (HH ’06), June 2006, pp. 56-59.
13	Gaurav J. Shah, P. Y. Chiou, Jian Gong, Aaron T. Ohta, Jeffrey B. Chou, Ming C. Wu, Chang-Jin “CJ” Kim, “Integrating Optoelectronic Tweezers for Individual Particle Manipulation with Digital Microfluidics Using Electrowetting-on-Dielectric (EWOD),” to be published in Proceedings IEEE 19th Annual International Conference on Micro Electro Mechanical Systems (MEMS ‘06), 2006.
12	P. Y. Chiou, Aaron T. Ohta, Ming C. Wu, “Continuous Optical Sorting of HeLa Cells and Microparticles Using Optoelectronic Tweezers,” in Proceesings IEEE/LEOS International Conference on Optical MEMS and Their Applications (OMEMS ’05), 2005, pp.83-84
11	P. Y. Chiou, Aaron T. Ohta, Ming C. Wu, “Optical Sorting Mechanism in Dynamic Electric Field Induced by Optoelectronic Tweezers,” in Proceeding of The International Conference on Bio-Nano-Informatics Fusion, July 2005.
10	A. T. Ohta, P. Y. Chiou, T. H. Han, J. C. Liao, U. Bhardwaj, E. R. B. McCabe, F. Yu, R. Sun, M. C. Wu, “Manipulation of live red and white blood cells via optoelectronic tweezers,” in Proceeding of The International Conf. on Bio-Nano-Informatics (BNI) Fusion, July 2005.
9	P. Y. Chiou, Aaron T. Ohta, Ming C. Wu,“ Microvision activated optical manipulation on microscopic particles,” to be published in Proceedings IEEE 18th Annual International Conference on Micro Electro Mechanical Systems (MEMS ‘05), 2005,pp. 682-685.
8	P. Y. Chiou, Aaron T. Ohta, M. C. Wu, “Toward all optical lab-on-a-chip system: optical manipulation of both microfluid and microscopic particles,” in Proceedings of SPIE - the International Society for Optical Engineering, AM266, Aug 2, 2004.
7	P. Y. Chiou, W. Wong, J. C. Liao, M. C. Wu, ”Cell addressing and trapping using novel optoelectronic tweezers,” in Proceedings IEEE 17th Annual International Conference on Micro Electro Mechanical Systems (MEMS ‘04), 2004, pp. 21-24.
6	A. T. Ohta, P. Y. Chiou, M. C. Wu, ”Dynamic DMD-Driven Optoelectronics Tweezers for Microscopic Particle Manipulation,” submitted to Conference on Lasers and Electro Optics/International Quantum Electronics Conference (CLEO ’04), 2004.
5	A. T. Ohta, P. Y. Chiou, M. C. Wu, “ Dynamic array manipulation of microscopic particles via optoelectronic tweezers,” in Proceedings of Solid-State Sensor, Actuator, and Microsystems Workshop (HH ’04), 2004, pp.216-219.
4	P. Y. Chiou, Z. Chang, M. C. Wu, “A novel optoelectronic tweezer using light induced dielectrophoresis,” in Proceesings IEEE/LEOS International Conference on Optical MEMS and Their Applications (OMEMS ’03), 2003, pp. 8-9.
3	P. Y. Chiou, Z. Chang, M. C. Wu, “Pico liter droplet manipulation based on a novel Continuous Opto-Electrowetting mechanism,” in Proceedings IEEE twelfth International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers ’03), 2003, pp. 557-562.
2	P. Y. Chiou, Z. Chang, M. C. Wu, “ Light actuated microfluidic system, ”in Proceedings IEEE 16th Annual International Conference on Micro Electro Mechanical Systems(MEMS ‘03), 2003, pp.355-358.
1	P. Y. Chiou, H. Moon, H. Toshiyoshi, C.J. Kim, M. C. Wu, ”Optical actuation of microfluidics based on Opto-Electrowetting,” in Proceedings of Solid-State Sensor, Actuator, and Microsystems Workshop (HH ’02), 2002, pp.269-272.